Prof Alan Irvine

  • Professor of Dermatology, Trinity College, Dublin
  • Consultant Dermatologist, Children’s Health Ireland


Alan graduated in Medicine from Queen’s University Belfast (QUB) in 1991. In 1998, he was awarded a research doctorate (MD) in Human Genetics, also from QUB. He completed Dermatology Training in Belfast in July 1999, followed by fellowships in Great Ormond Street Children’s Hospital, and Children’s Memorial Hospital Chicago, where he was a Fulbright Scholar.

He was appointed Consultant Dermatologist (Attending Physician) in Children’s Health Ireland at Crumlin (CHI at Crumlin) and St. James’s Hospital, Dublin, Ireland in October 2002.

He is Professor in Dermatology, Trinity College Dublin.

His primary research focus is on the pathogenesis of atopic dermatitis (AD), the most common chronic inflammatory disease of children in the developed world.

His work on the genetics of atopic dermatitis with long term collaborative partner Irwin McLean has helped refocus attention on the role of the skin barrier in the pathogenesis of this disease and of allergic disease in general. He is funded by the National Children’s Research Centre and the Wellcome Trust, and has attracted approximately €11M funding to date. The Irvine group has developed one of the largest case collections of childhood AD; this case collection has been used to discover several new genetic insights into this common disease.


Atopic Dermatitis.
Langan S, Alan D Irvine AD, Weidinger S. The Lancet, 2020 Aug 1;396(10247):345-360. doi: 10.1016/S0140-6736(20)31286-1. PMID: 32738956

Report from the National Institute of Allergy and Infectious Diseases Workshop on “Atopic Dermatitis and the Atopic March: Mechanisms and Interventions”
Davidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M; Journal of Allergy and Clinical Immunology. 2019 Jan 9. pii: S0091-6749(19)30014-4. doi: 10.1016/j.jaci.2019.01.003. [Epub ahead of print] PMID: 30639346